Dominique began honing her skills unprofessionally as a civil servant on the night shift as a postal worker at the now infamous Brentwood Postal facility in her native Washington D.C. Boredom with the job gave way to open mic nights at local clubs, at the behest of friends and co-workers. Dominique immediately gained a reputation for telling it like it is and unknowingly garnered a loyal following. Washington's uppity audiences gravitated toward her mixture of politics, street culture and current events. Her strong presence and a bravado rarely seen in female comics quickly gained the attention of the producers of HBO's Russell Simmons's Def Comedy Jam, the show that changed comedy forever. She went from shuffling mail to working with the likes of Chris Rock in no time. Sensing that she had outgrown D.C.'s small comedy scene, she moved to the Bronx and became a fixture at the clubs in New York. Places like the Comic Strip and Stand Up New York served as testing grounds for her new material. By chance, she met SNL's Tracy Morgan, who made Dominique his opening act for his run at Caroline's on Broadway. The two formed a friendship and have been working together ever since. Being Tracy's feature, however, wasn't enough to keep the bills paid. So Dominique became what she calls a "hustler," performing all over the country to make ends meet.

Upon her arrival in Los Angeles, Dominique began making the rounds in Hollywood's comedy clubs as well as the smaller, lesser-known spots in LA. Since that time, she has enjoyed a run on the highly successful Mike Epps On the Edge Tour and numerous television appearances, including Byron Allen’s Comics Unleashed, the Tom Joyner Sky Show, HBO’s On-Demand Ask-A-Sista and Big Black Love. She has also participated in Urban Internationals Comedy Arts Festival, better known as "Laffapalooza,” as well as the Bay Area Comedy Competition in Oakland. With several years of study under her belt, she added acting to her resume when she landed a part in the critically acclaimed indie Thirty Years to Life and is represented commercially by Innovative Artist (LA), who asked her to join their roster after one of their agents just happened to catch her act one night. These are the things to know about Dominique: she's a class act from stage to film; she's a woman with a strong point of view and a strong way of telling it; and she's ready for whatever those in the know throw her way.