Joyner is originally from Pittsburgh, Pennsylvania and now makes his home in Santa Monica, California.

Joyner was formerly the host of MTV's 1/2 Hour Comedy Hour. He has appeared many times on the Late Show with David Letterman, Showtime's Aspen Rooftop Comedy Festival, as well as his own One Night Stand special on HBO.

Joyner has been the opening act for numerous tours and concerts, Chris Rock: Kill the Messenger - London, New York, Johannesburg and Jerry Seinfeld's nationwide tour.

Joyner made his film/acting debut as a cab driver with passengers Ted Danson, Steve Guttenberg, and Tom Selleck in Touchstone Pictures' smash hit, 3 Men and a Baby. He starred as Tom in Hangin' with the Homeboys from New Line Cinema. He appeared in Down to Earth and the cult classic, Pootie Tang, with the famous quote, "Sine your pitty on the runny kine!" He was also in various episodes of Everybody Hates Chris and The Chris Rock Show. He can be seen in the motion picture, Bucky Larson: Born to Be a Star.